Treatment of paraproctitis with antibiotics

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Updated: 06.06.2024
Antibiotics for paraproctitis

Etiotropic treatment of paraproctitis

Paraproctitis is an inflammatory condition of the connective tissue around the rectum caused by various types of bacteria. Effective treatment for this condition involves the use of antibiotics to kill the pathogenic bacteria. Antibiotics used for paraproctitis come from different groups and are available in different forms. Only a doctor can prescribe these medications based on the severity of the disease.

Causes of the disease

The main cause of the inflammatory process in the connective tissue surrounding the rectum is the activity of various pathogenic bacteria. Some of the most common microorganisms that can cause this are staphylococci, Escherichia coli, Klebsiella and Proteus. Their penetration into the connective tissue fibers often leads to a breach in the mucosal integrity of the lower intestine, resulting in fissures and erosions. Paraproctitis can also be a complication of hemorrhoids, especially in the second and third stages of their development.

Antibiotic treatment

The use of antibacterial agents forms the basis of the etiotropic treatment of infectious and inflammatory diseases of the perirectal region, which aims to destroy pathogenic bacterial agents. For this purpose, different types of such medications are used, and the choice of the appropriate medication is made by the treating physician. The independent use of these medications can lead to the development of bacterial resistance, as well as various complications, such as the formation of a perirectal abscess, a cavity surrounded by connective tissue and filled with pus.


The main symptom of inflammation of the connective tissue surrounding the rectum is the development of intense pain in the area affected by the condition. This pain is often exacerbated during the act of defecation or while the person is sitting, and it can have a throbbing quality. Properly administered antibiotics can significantly reduce the severity of these symptoms, indicating the effectiveness of the treatment.

What antibiotics to take?

The choice of antibiotics is made by a doctor based on the suspected cause of the infection (empirically) or based on data from bacterial tests that determine the sensitivity of a specific pathogen to different groups of antibiotics. Currently, the most common groups used are:

  • Semi-synthetic penicillins.
  • Cephalosporins.
  • Macrolides.

They can also be administered in different forms. Depending on the severity of inflammation, they may be used as antibiotic suppositories for proctitis, tablets or capsules, or in a parenteral form (injections).

If, based on clinical, laboratory, and instrumental examination data, a paraproctitis diagnosis has been made, the attending physician will determine which antibiotics to use, their dosage, and the duration of their course. Independent and unsupervised use of antibacterial agents can lead to the subsequent development of complications.

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